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曹新月作为一个从小生长的大山的女孩，想要出人头地离开大山，只能靠自己努力。她成功拿下清北大学的录取通知书，但当她喜气洋洋的带着通知书回家向父亲报喜的时候，觊觎她已久的恶霸村长却已经带着一伙人气势汹汹地赶到了曹家，试图将她永远留在大山中……。生化制药厂的老板Franklin提供大量资金供让Susan McAlester博士研究抗老年痴呆症的药物。Susan和研究小组在设备精良的海底研究中心，提取鲨鱼脑中蛋白质，注入坏死的人类脑细胞。为了可以提取到更多的鲨鱼脑蛋白，Susan也同时加大了鲨鱼们的脑容量。这一举动让本来作为试验品的鲨鱼们变得更为强壮和聪明。鲨鱼专家Carter因和鲨鱼们朝夕相处时发现了鲨鱼们的异样，并向Susan提出了警告，却得到了Susan的无视。终于，在最后一次实验中，那些曾经沦为人类试验品的凶残鲨鱼们向人类展开报复……。When a casino owning dog named Charlie is murdered by his rival Carface, he finds himself in Heaven basically by default since all dogs go to heaven. However, since he wants to get back at his killer, he cons his way back to the living with the warning that doing that damns him to Hell. Once back, he teams with his old partner, Itchy to prep his retaliation. He also stumbles on to an orphan girl who can talk to the animals, thus allowing him to get the inside info on the races to ensure his wins。